Fig. 7. Expression of renal TRPC channels in wild-type (WT) and Trpc6^-/- mice. Renal mRNA levels of (A) transient receptor potential cation channel 1 (TRPC1), (B) TRPC2 (C) TRPC3 (D) TRPC4 (E) TRPC5 and (F) TRPC6 in sham-operated groups and in UUO-operated groups. Renal mRNA expression data were determined in n=5 each for sham-operated WT and Trpc6^-/- mice, n=9 for UUO-operated WT mice and n=8 for UUO-operated Trpc6^-/- mice. The relative standard curve method was used for relative quantification. All data are means ± SD., ns p>0.05, **p<0.01, ***p<0.001, ****p<0.0001. ns, not significant; n.d., not detected.